The world's largest single-dish radio telescope at the U.S. National Astronomy and Ionosphere Center (NAIC) in Puerto Rico has been involved in cutting-edge science for over 40 years, including radar imaging of planets and asteroids, faint hydrogen surveys of distant galaxies, and Nobel Prize work using pulsars to test general relativity. I will describe a few highlights of recent work, especially projects using the ALFA multibeam receiver to perform new and exquisite surveys of our home galaxy.